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Experimental studies using cell cultures and animal models have demonstrated that ethanol exposure produces a significant accumulation of ROS and lipid peroxidation, hallmarks of ferroptosis [170], [171], [172], [173], [174]

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In neurodegenerative diseases and in aging they organize the response to OS and damage to DNA and are related to the functionality of the respiratory machinery and the production of ROS in different tissues (Huang et al., 2010)